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Showing posts from June, 2025

Novel Perspective of Regulating p53/Bcl2/Caspase-3 via In vitro Targeted AFP Gene Knocks Out in HepG2 Cells Using CRISPR/Cas9 Editing Tool

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Bibliographic Information Authors: Khorshed F.; Medhat A.M.; Hamdy G.M.; El-Dabaa E.; Hammad H.; Elhameed H.A.H.A.; Saber M. Journal: Current Gene Therapy Publisher: Bentham Science Publishers Publication Date: 12 June 2025 ISSN: 15665232 DOI: 10.2174/0115665232366303250529164610 Scopus: View on Scopus PubMed: 40511828 Document Type: Article Authors and Affiliations Khorshed F., Department of Biochemistry & Molecular Biology, Theodor Bilharz Research Institute, Giza, Egypt; Medhat A.M., Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt; Hamdy G.M., Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt; El-Dabaa E., Department of Biochemistry & Molecular Biology, Theodor Bilharz Research Institute, Giza, Egypt; Hammad H., Department of Biochemistry & Molecular Biology, Theodor Bilharz Research Institute, Giza, Egypt; Elhameed H.A.H.A., Department of Biochemistry, Faculty of Science, Zagazig ...
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Impact of semaglutide on health outcomes and mood in obese heart failure patients: a retrospective analysis

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Bibliographic Information Authors: Balata M.; Sugiura A.; Hassan M.; Rady M.; Christoph M.; Ibrahim K.; Becher M.U.; Youssef A. Journal: Clinical Research in Cardiology Publisher: Springer Science and Business Media Deutschland GmbH Publication Date: 10 June 2025 Volume / Issue: Volume 115 / Issue 9 Pages: 1533–1542 ISSN: 18610684 DOI: 10.1007/s00392-025-02694-5 Scopus: View on Scopus PubMed: 40493069 Document Type: Article Authors and Affiliations Balata M., University Hospital Bonn, Venusberg-Campus 1, Bonn, 53127, Germany, Department of Internal Medicine and Cardiology, University Hospital Rostock, Ernst-Heydemann-Straße 6, Rostock, 18057, Germany; Sugiura A., University Hospital Bonn, Venusberg-Campus 1, Bonn, 53127, Germany; Hassan M., Department of Immunology, Theodor Bilharz Research Institute, Giza, Egypt; Rady M., Department of Internal Medicine and Cardiology, City Chemnitz Teaching Hospital, Medical Campus of the Technical University of Dresden, Bü...
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Bacillus clausii spores maintain gut homeostasis in murine ulcerative colitis via modulating microbiota, apoptosis, and the TXNIP/NLRP3 inflammasome cascade

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Bibliographic Information Authors: Salem M.B.; El-Lakkany N.M.; Hammam O.A.; Seif el-Din S.H. Journal: Toxicology Reports Publisher: Elsevier Inc. Publication Date: June 2025 Volume / Issue: Volume 14 Article No.: 101858 ISSN: 22147500 DOI: 10.1016/j.toxrep.2024.101858 Scopus: View on Scopus Document Type: Article Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations Salem M.B., Pharmcology Department, Theodor Bilharz Research Institute, Giza, Egypt; El-Lakkany N.M., Pharmcology Department, Theodor Bilharz Research Institute, Giza, Egypt; Hammam O.A., Pathology Department, Theodor Bilharz Research Institute, Giza, Egypt; Seif el-Din S.H., Pharmcology Department, Theodor Bilharz Research Institute, Giza, Egypt Abstract Ulcerative colitis (UC), a persistent immune-mediated disorder lacking effective treatment, is distinguished by gut microbiota dysbiosis, abnormal activation of the NLRP3 inflammasome pathway, and apoptosis. De...
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