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Showing posts from June, 2018

Bioprospecting certain freshwater-derived fungi for phenolic compounds with special emphasis on antimicrobial and larvicidal activity of methyl gallate and p-coumaric acid

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Bibliographic Information Authors: Abdel-Wareth M.T.A.; Ghareeb M.A. Journal: Egyptian Journal of Chemistry Publisher: NIDOC (Nat.Inform.Document.Centre) Publication Date: 22 June 2018 Volume / Issue: Volume 61 / Issue 5 Pages: 773–784 ISSN: 4492285 DOI: 10.21608/ejchem.2018.3237.1276 Scopus: View on Scopus Document Type: Article Access: All Open Access; Bronze Open Access Authors and Affiliations Abdel-Wareth M.T.A., Environmental Research and Medical Malacology Department, Theodor Bilharz Research Institute, Giza, Egypt; Ghareeb M.A., Medicinal Chemistry, Biochemistry and Molecular Biology Department, Theodor Bilharz Research Institute, Giza, Egypt Abstract FUNGI naturally produce secondary metabolites which have been investigated as biologically active compounds. This work aimed at exploring phenolic compounds profile of three fresh-water derived fungi, and investigating the antimicrobial and larvicidal activity of methyl gallate and p-coumaric acid as ...

Significance of pSmad2/3 and Smad4 in hepatitis C virus-related liver fibrosis and hepatocellular carcinoma

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Bibliographic Information Authors: Moussa M.M.; Helal N.S.; Youssef M.M. Journal: APMIS Publisher: Blackwell Munksgaard Publication Date: 20 June 2018 Volume / Issue: Volume 126 / Issue 6 Pages: 477–485 ISSN: 9034641 DOI: 10.1111/apm.12844 Scopus: View on Scopus PubMed: 29924446 Document Type: Article Authors and Affiliations Moussa M.M., Pathology Department, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt; Helal N.S., Pathology Department, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt; Youssef M.M., Pharmacology and Toxicology Department, Egyptian-Russian University, Cairo, Egypt, Graduate School, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan Abstract Chronic hepatitis C (CHC) is a major public health problem, especially in Egypt. Risk of hepatocellular carcinoma (HCC) development increases as hepatitis C virus (HCV)-related liver diseases progress. Smads act as substrates for the transforming growth fa...

Colonic stem cells expression of Lgr5 and CD133 proteins as predictive markers in colorectal cancer among Egyptian patients

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Bibliographic Information Authors: Rosiq S.; Hammam O.; Abdelalim A.; Anas A.; Khalil H.; Amer M. Journal: Open Access Macedonian Journal of Medical Sciences Publisher: Open Access Macedonian Journal of Medical Sciences Publication Date: 7 June 2018 Volume / Issue: Volume 6 / Issue 6 Pages: 968–974 ISSN: 18579655 DOI: 10.3889/oamjms.2018.208 Scopus: View on Scopus Document Type: Article Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations Rosiq S., Tropical Medicine Department, Al Azhar University, Cairo, Egypt; Hammam O., Pathology Department, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt; Abdelalim A., Tropical Medicine Department, Al Azhar University, Cairo, Egypt; Anas A., Hepato-Gastroenterology, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt; Khalil H., Pathology Department, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt; Amer M., Tropical Medicine Department, Nasser Institute Hospital, Cairo,...

Liver protective effects of renin-angiotensin system inhibition have no survival benefits in hepatocellular carcinoma induced by repetitive administration of diethylnitrosamine in mice

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Bibliographic Information Authors: Saber S.; Mahmoud A.; Helal N.; El-Ahwany E.; Abdelghany R. Journal: Open Access Macedonian Journal of Medical Sciences Publisher: Open Access Macedonian Journal of Medical Sciences Publication Date: 6 June 2018 Volume / Issue: Volume 6 / Issue 6 Pages: 955–960 ISSN: 18579655 DOI: 10.3889/oamjms.2018.167 Scopus: View on Scopus Document Type: Article Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations Saber S., Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt; Mahmoud A., Department of Pharmacology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt; Helal N., Pathology Department, Theodor Bilharz Research Institute, Giza, Egypt; El-Ahwany E., Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt; Abdelghany R., Department of Pharmacology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt Abstract BACKGR...

Renin–angiotensin system inhibition ameliorates CCl4-induced liver fibrosis in mice through the inactivation of nuclear transcription factor kappa B

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Bibliographic Information Authors: Saber S.; Mahmoud A.A.A.; Helal N.S.; El-Ahwany E.; Abdelghany R.H. Journal: Canadian Journal of Physiology and Pharmacology Publisher: Canadian Science Publishing Publication Date: June 2018 Volume / Issue: Volume 96 / Issue 6 Pages: 569–576 ISSN: 84212 DOI: 10.1139/cjpp-2017-0728 Scopus: View on Scopus PubMed: 29425464 Document Type: Article Authors and Affiliations Saber S., Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt; Mahmoud A.A.A., Department of Pharmacology, Faculty of Pharmacy, Zagazig University, Zagazig, 44519, Egypt, Department of Pharmacology, Oman Pharmacy Institute, Ministry of Health, Muscat, Oman; Helal N.S., Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt; El-Ahwany E., Department of Immunology, Theodor Bilharz Research Institute, Giza, Egypt; Abdelghany R.H., Department of Pharmacology, Faculty of Pharmacy, Zagazig Univ...

A potential antibacterial wound dressing of cefadroxil chitosan nanoparticles in situ gel: Fabrication, in vitro optimization and in vivo evaluation

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Bibliographic Information Authors: Basha M.; AbouSamra M.M.; Awad G.A.; Mansy S.S. Journal: International Journal of Pharmaceutics Publisher: Elsevier B.V. Publication Date: June 2018 Volume / Issue: Volume 544 / Issue 1 Pages: 129–140 ISSN: 3785173 DOI: 10.1016/j.ijpharm.2018.04.021 Scopus: View on Scopus PubMed: 29655798 Document Type: Article Authors and Affiliations Basha M., Pharmaceutical Technology Department, National Research Centre, Cairo, 12311, Egypt; AbouSamra M.M., Pharmaceutical Technology Department, National Research Centre, Cairo, 12311, Egypt; Awad G.A., Chemistry of Natural and Microbial Product Department, National Research Centre, Cairo, 12311, Egypt; Mansy S.S., ElectronMicroscopy Research Department, Theodor Bilharz Research Institute, Cairo, Egypt Abstract Wound healing following skin injury is a natural phenomenon that usually lacks quality, rapidity, and aesthetics. Thus, the purpose of this study was to fabricate a new easily ap...