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Showing posts from January, 2026

Evaluation of physcion isolated from endophytic Aspergillus fumigatus ASH3 as an antiviral agent against coxsackievirus B4 and herpes simplex virus type 1: in silico-supported invitro study

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Bibliographic Information Authors: Bukhari K.; Elkhouly H.I.; Hasan S.F.; Soliman A.G.; Selim H.M.R.M.; Sidkey N.M.; El-Hosainy A.; Saleh A.; Fahim A.M.; Ghareeb M.A.; Hamed A.A. Journal: Folia Microbiologica Publisher: Springer Science and Business Media B.V. Publication Date: 31 January 2026 ISSN: 155632 DOI: 10.1007/s12223-025-01389-8 Scopus: View on Scopus Document Type: Article Authors and Affiliations Bukhari K., Department of Microbiology and Parasitology, College of Veterinary Medicine, King Faisal University, Hofuf, Al-Ahsa, 36362, Saudi Arabia; Elkhouly H.I., Botany and Microbiology Department, Faculty of Science, Al-Azhar University (Girls Branch), P.O. 11754, Cairo, Yossuf Abbas st, Nasr City, Egypt; Hasan S.F., Botany and Microbiology Department, Faculty of Science, Al-Azhar University (Girls Branch), P.O. 11754, Cairo, Yossuf Abbas st, Nasr City, Egypt; Soliman A.G., Biotechnology Program, Faculty of Agriculture, Ain Shams University, Cairo, Egypt; Se...

Thiophene-Pyridine Derivatives as Potential Anti-Proliferative and Anti-Inflammatory Apoptotic Agents: Synthesis, In Vitro Evaluation, Molecular Docking, and Dynamic Simulations

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Bibliographic Information Authors: El-Bana G.G.; Salman F.H.; Mahmoud F.R.; F. El-Sayed A.; A. Ismail M. Journal: Polycyclic Aromatic Compounds Publisher: Taylor and Francis Ltd. Publication Date: 29 January 2026 Volume / Issue: Volume 46 / Issue 5 Pages: 760–790 ISSN: 10406638 DOI: 10.1080/10406638.2026.2620419 Scopus: View on Scopus Document Type: Article Authors and Affiliations El-Bana G.G., Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt, Mansoura University Student’s Hospital, Mansoura University, Mansoura, Egypt; Salman F.H., Biochemistry and Molecular Biology Department, Theodor Bilharz Research Institute (TBRI), Giza, Egypt; Mahmoud F.R., Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt; F. El-Sayed A., Microbial Genetics Department, Biotechnology Research Institute, National Research Centre, Giza, Egypt, Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo, Egypt; A. Isma...

Colonization with Carbapenemase producing Enterobacterales (CPE) and associated alteration in microbiota composition in a tertiary care hospital in Egypt

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Bibliographic Information Authors: El-Defrawy I.; Khaled M.; El-Far A.; El-Shenawy A.; Salem D.; Gamal D.; Fam N.; Sayed H.A.; Hayek N.N.; Elrefaiy M.A.; Ray A.E.; Soliman N.S.; Soliman M.S.; El-Kholy A.A. Journal: BMC Microbiology Publisher: BioMed Central Ltd Publication Date: 27 January 2026 Volume / Issue: Volume 26 / Issue 1 Article No.: 58 ISSN: 14712180 DOI: 10.1186/s12866-025-04575-3 Scopus: View on Scopus PubMed: 41588318 Document Type: Article Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations El-Defrawy I., Microbiology Department, Theodor Bilharz Research Institute (TBRI), P.O box 12411, 30 Imbaba, Giza, Egypt; Khaled M., Microbiology Department, Theodor Bilharz Research Institute (TBRI), P.O box 12411, 30 Imbaba, Giza, Egypt; El-Far A., Microbiology Department, Theodor Bilharz Research Institute (TBRI), P.O box 12411, 30 Imbaba, Giza, Egypt; El-Shenawy A., Microbiology Department, Theodor Bilharz Research Inst...

Evaluation of CaSR rs1801725 and circulating miRNA-21-5p and miRNA-124-3p expression in chronic kidney disease-mineral and bone disorder patients

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Bibliographic Information Authors: Osman E.A.; El-shishtawy S.H.; Khanany F.M. Journal: Egyptian Journal of Medical Human Genetics Publisher: Springer Nature Publication Date: 17 January 2026 Volume / Issue: Volume 27 / Issue 1 Article No.: 6 ISSN: 11108630 DOI: 10.1186/s43042-026-00838-4 Scopus: View on Scopus Document Type: Article Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations Osman E.A., Clinical Chemistry Department, Theodor Bilharz Research Institute, Giza, Egypt; El-shishtawy S.H., Nephrology Department, Theodor Bilharz Research Institute, Cairo, Egypt; Khanany F.M., Clinical Chemistry Department, Theodor Bilharz Research Institute, Giza, Egypt Abstract Background: Chronic kidney disease-mineral and bone disorder (CKD-MBD) has been a prominent consequence of end-stage renal disease (ESRD), increasing cardiovascular risk and skeletal fragility. Emerging research shows that genetic and epigenetic variables play a...

Potential of the Snail-Parasitic Nematode Phasmarhabditis eagyptiaca Azzam 2023 to Control Terrestrial and Freshwater Snails Under Laboratory and Field Conditions

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Bibliographic Information Authors: Azzam K.M.; El Husseini M.M.; El-Hommossany K. Journal: Egyptian Journal of Aquatic Biology and Fisheries Publisher: Egyptian Society for the Development of Fisheries and Human Health Publication Date: 4 January 2026 Volume / Issue: Volume 30 / Issue 1 Pages: 167–184 ISSN: 11106131 DOI: 10.21608/ejabf.2026.450460.7185 Scopus: View on Scopus Document Type: Article Access: All Open Access; Gold Open Access Authors and Affiliations Azzam K.M., Plant Protection Research Institute, Agricultural Research Center, Dokki, Giza, Egypt; El Husseini M.M., Center of Biological Control, Faculty of Agriculture Cairo University, Egypt; El-Hommossany K., Theodor Bilharz Research Institute, Egypt Abstract In Egypt, over 20 species of freshwater snails, 16 land snail species, and three slugs attack approximately 64 plant types. All terrestrial and freshwater snails cause significant damage to crops, in addition to serving as intermediate ho...

Development and validation of qPCR assay targeting COWP conserved region for sensitive detection and quantification of Cryptosporidium infections

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Bibliographic Information Authors: Okasha H.; El-Kalamawy H.A.; Mashaal A.R.; El-Wakil E.S. Journal: Veterinary Parasitology Publisher: Elsevier B.V. Publication Date: January 2026 Volume / Issue: Volume 341 Article No.: 110653 ISSN: 3044017 DOI: 10.1016/j.vetpar.2025.110653 Scopus: View on Scopus PubMed: 41259837 Document Type: Article Authors and Affiliations Okasha H., Biochemistry and Molecular Biology Department, Theodor Bilharz Research Institute, Giza, Egypt; El-Kalamawy H.A., Biochemistry and Molecular Biology Department, Theodor Bilharz Research Institute, Giza, Egypt; Mashaal A.R., Hepato-Gastroenterology Department, Theodor Bilharz Research Institute, Giza, Egypt; El-Wakil E.S., Parasitology Department, Theodor Bilharz Research Institute, Giza, Egypt Abstract Background: Cryptosporidium is a significant food and waterborne protozoan parasite. Molecular diagnosis and quantification play a crucial role in diagnosing infections, as well as in under...

Integrated genetic and epigenetic biomarker landscapes in hepatocellular carcinoma: From molecular mechanisms to translational precision oncology

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Bibliographic Information Authors: Aly D.M.; Fteah A.M.; Elrefaiy M.A.; Seddik H.E. Journal: Gene Reports Publisher: Elsevier Inc. Publication Date: 2026 Volume / Issue: Volume 45 Article No.: 102597 ISSN: 24520144 DOI: 10.1016/j.genrep.2026.102597 Scopus: View on Scopus Document Type: Review Authors and Affiliations Aly D.M., Department of Clinical Chemistry, Theodor Bilharz Research Institute, Egypt; Fteah A.M., Department of Clinical Chemistry, Theodor Bilharz Research Institute, Egypt; Elrefaiy M.A., Hepato-gastroenterology Department, Theodor Bilharz Research Institute, Egypt; Seddik H.E., Hepato-gastroenterology Department, Theodor Bilharz Research Institute, Egypt Abstract Hepatocellular carcinoma (HCC) remains a formidable global health challenge, characterized by profound molecular heterogeneity and dismal survival rates when diagnosed at advanced stages. Despite extensive discovery of genetic and epigenetic alterations in hepatocellular carcinoma, ...

Ticagrelor attenuates cholestasis-induced liver fibrosis by inhibiting S1PR2-dependent Akt/ERK signaling, NLRP3 inflammasome activation

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Bibliographic Information Authors: El-Maadawy W.H.; Amer M.; Mostafa A.; Hassany A.A.; Shafie N.S.; Lethy A.W.; El-Ahwany E.; Hafiz E. Journal: International Immunopharmacology Publisher: Elsevier B.V. Publication Date: January 2026 Volume / Issue: Volume 168 Article No.: 115834 ISSN: 15675769 DOI: 10.1016/j.intimp.2025.115834 Scopus: View on Scopus PubMed: 41240716 Document Type: Article Authors and Affiliations El-Maadawy W.H., Department of Pharmacology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba (P.O. 30), Giza, 12411, Egypt; Amer M., Department of Bioinformatics and Genomics, College of Biotechnology, Misr University for Science and Technology (MUST), Giza, Egypt; Mostafa A., Department of General Surgery, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba (P.O. 30), Giza, 12411, Egypt; Hassany A.A., Department of Bioinformatics and Genomics, College of Biotechnology, Misr University for Science and Technology (MUST), Giza, Egyp...

Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection

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Bibliographic Information Authors: Hassan Y.M.; El-Tantawi H.; Ali I.R.; Attia M.S. Journal: RSC Advances Publisher: Royal Society of Chemistry Publication Date: 2026 Volume / Issue: Volume 16 / Issue 30 Pages: 27358–27373 ISSN: 20462069 DOI: 10.1039/d6ra02425d Scopus: View on Scopus Document Type: Review Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations Hassan Y.M., Department of Zoology, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt; El-Tantawi H., Department of Zoology, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt; Ali I.R., Department of Immunology and Treatment Evaluation, Theodore Bilharz Research Institute, Giza, Egypt; Attia M.S., Chemistry Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia Abstract Cancer remains one of the foremost global health challenges, accounting for approximately 10 million dea...

Novel Nano-Quantum Dot Sandwich Enzyme Linked Immunosorbent Assay for Diagnosis of Human Fascioliasis

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Bibliographic Information Authors: Hamza H.T.; Mashaal A.; Aly I.R. Journal: Biotechnology and Bioengineering Publisher: John Wiley and Sons Inc Publication Date: 2026 Volume / Issue: Volume 123 / Issue 6 Pages: 1570–1580 ISSN: 63592 DOI: 10.1002/bit.70193 Scopus: View on Scopus PubMed: 41863541 Document Type: Article Authors and Affiliations Hamza H.T., Biology Department, College of Science, Jouf University, Sakaka, Saudi Arabia; Mashaal A., Immunology, Zoology & Entomology Department, Faculty of Science (for Girls), Al-Azhar University, Cairo, Egypt; Aly I.R., Parasitology Department, Theodor Bilharz Research Institute, Giza, Egypt Abstract Novel laboratory-developed immunodiagnostic microarray based on microbeads encoded with quantum dots (QDs) has been developed and validated for quantitative detection of human fascioliasis in serum and stool samples. The present study aimed to prepare and purify F. gigantica excretory/secretory antigen and conjug...

Correlation Between Chemerin Levels and Diagnosis of Diabetic Nephropathy: A Case-Control Study

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Bibliographic Information Authors: Attia Elsayed F.M.; Salem S.M.; Attia Elbadry M.M.; Omar A.; Alwaseef M.A.E.; Mohamed E.S.; Boshra M.S.; Ismail H.A.M.; Zidan M.H.S.; Ali O.S.H.; Hamed O.A.E.; Abd El Fattah M.Y.; Rashad D.F.; Rashed R.M.I.; Kayed A.A.A.; Azel L.H.; Saleh R.H.A.A.; Moneer A.H.; Mahrose H.K.A.; Da A. Journal: Clinica Terapeutica Publisher: Societa Editrice Universo Publication Date: 2026 Volume / Issue: Volume 177 / Issue 3 Pages: 554–562 ISSN: 99074 DOI: 10.7417/CT.2026.2041 Scopus: View on Scopus PubMed: 42047143 Document Type: Article Authors and Affiliations Attia Elsayed F.M., Internal Medicine Department, Faculty of Medicine, Zagazig University, Egypt; Salem S.M., Internal Medicine Department, Faculty of Medicine, Zagazig University, Egypt; Attia Elbadry M.M., Family Medicine Department, Faculty of Medicine, Zagazig University, Egypt; Omar A., Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt; Alwa...

Closing the Diagnostic-Therapeutic Gap in Post-Cholecystectomy Biliary Complications: Impact of Endoscopic Ultrasound on Diagnostic Reclassification and Therapeutic Decision-Making in a Multidisciplinary Hepatopancreatobiliary Pathway

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Bibliographic Information Authors: Ghoname M.; Mohamed D.M.A.; Mahran A.A.S.; Abdelmalik A.; Ghazy A.M.; Aboismail A.A.M.; Youssef M.Z.; Ali R.F.; Shaaban A.A.A.; Helmy H.A.; Kandyl M.A.-H.; El-Seaidy M.A.A.E.A.; Hegab S.M.E.A.; Mohamed M.S.E.; Mashaal S.A. Journal: Natural Resources for Human Health Publisher: Visagaa Publishing House Publication Date: 2026 Volume / Issue: Volume 6 / Issue 2S Pages: 749–758 ISSN: 25831194 Scopus: View on Scopus Document Type: Article Authors and Affiliations Ghoname M., Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, Al-Azhar University, Cairo, Egypt; Mohamed D.M.A., Department of Gastroenterology and Hepatology, Theodor Bilharz Research Institute, Giza, Egypt, Faculty of Medicine, Ain Shams University, Cairo, Egypt; Mahran A.A.S., Department of Internal Medicine, Faculty of Medicine, New Valley University, New Valley, Egypt; Abdelmalik A., Department of Hepatology, Gastroenterology and I...

Holmium versus bipolar en bloc transurethral resection of urinary bladder tumors: a randomized controlled trial

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Bibliographic Information Authors: Higazy A.; Lotfy A.; Tawfeek A.M.; Ali A.; Radwan A. Journal: Central European Journal of Urology Publisher: Polish Urological Association Publication Date: 2026 Volume / Issue: Volume 79 / Issue 2 Pages: 111–117 ISSN: 20804806 DOI: 10.5173/ceju.2025.0268 Scopus: View on Scopus Document Type: Article Access: All Open Access; Green Open Access Authors and Affiliations Higazy A., Ain Shams University, Cairo, Egypt; Lotfy A., Ain Shams University, Cairo, Egypt; Tawfeek A.M., Ain Shams University, Cairo, Egypt; Ali A., Royal United Hospital, Bath, United Kingdom, Theodor Bilharz Research Institute, Giza, Egypt; Radwan A., Ain Shams University, Cairo, Egypt Abstract Introduction The study evaluated the safety, efficacy, and pathological outcomes of holmium laser en bloc resection of bladder tumor (HoL-ERBT) vs bipolar en bloc resection of bladder tumor (Bp-ERBT). Material and methods Adult patients with bladder masses less tha...

Diagnostic accuracy of the Fibrosis-4 (FIB-4) index for advanced liver fibrosis in Qatari patients with MASLD: Comparison with liver biopsy and FibroScan

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Bibliographic Information Authors: Derbala M.; Obeidat I.M.; Abualsuod R.; Draidi M.; Selim N.; Maatoug J.; Elkalamawi A. Journal: Qatar Medical Journal Publisher: HBKU Press Publication Date: 2026 Volume / Issue: Volume 2026 / Issue 2 Article No.: 32 ISSN: 2538253 DOI: 10.5339/qmj.2026.32 Scopus: View on Scopus Document Type: Article Access: All Open Access; Gold Open Access; Green Open Access Authors and Affiliations Derbala M., Gastroenterology and Hepatology, Hamad Medical Corporation, Doha, Qatar, Theodore Bilharz Research Institute, Warraq Al Hadar, Egypt, Weill Cornell Medical College, Ar-Rayyan, Qatar; Obeidat I.M., Gastroenterology and Hepatology, Hamad Medical Corporation, Doha, Qatar; Abualsuod R., Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar; Draidi M., Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar; Selim N., Community and Preventive Medicine Department, Primary Health Care Corporation, Doha, Qatar; M...

Mentha Spicata Extract Could Overcome Helicobacter Pylori By Inhibiting Urease and HP1043 – Docking, ADMET and Molecular Dynamics Simulation Study

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Bibliographic Information Authors: Alsedfy M.Y.; Ghanem A.; Sewar M.; Nasr S.M.; Salama M.M.; Said A.H. Journal: Egyptian Journal of Chemistry Publisher: National Information and Documentation Centre Publication Date: 2026 Volume / Issue: Volume 69 / Issue 10 Pages: 215–232 ISSN: 4492285 DOI: 10.21608/ejchem.2026.453146.12789 Scopus: View on Scopus Document Type: Article Authors and Affiliations Alsedfy M.Y., Faculty of Applied Health Sciences, Sphinx University, New Assiut, Egypt, Electronics and Nano Devices Lab, Faculty of Science, South Valley University, Qena, 83523, Egypt, Egyptian Cancer Research Network, Academy of Scientific Research and Technology, Cairo, Egypt; Ghanem A., School of Biotechnology, Badr University in Cairo, Cairo, Badr City, 11829, Egypt; Sewar M., School of Biotechnology, Badr University in Cairo, Cairo, Badr City, 11829, Egypt; Nasr S.M., Department of Biochemistry and Molecular Biology, Theodor Bilharz Research Institute, Giza, 1241...

Exploring the link between D-dimer and major adverse cardiovascular events in smokers with type 2 diabetes mellitus

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Bibliographic Information Authors: Omar A.; Elmalah A.A.; Elkenany N.M.; Elmahdy H.K.; Agiba N.A.; Elsherbiny E.A.; Abdellah M.I.; Elshehabi A.A.M.; Alwaseef M.A.E.; Shaheen M.A.E.; Hegazy H.A.; Mekheimar M.A.M.; Alsayyad M.M.A.A.; Ajlan M.A.; Kassem I.A.; Mahrose H.K.A.; Said S.R.A.; Metwally M.M.M.; Hassan Z.S.Y.; Mayah F.I.I.; Khedr M.A.E.; Muhammad A.A.A.; Ahmed A.H.M.Z.; Abdo A.A.F.; El-Mahalawy M.H.; Elsheikh E. Journal: Journal of Medicinal and Pharmaceutical Chemistry Research Publisher: Sami Publishing Company Publication Date: 2026 Volume / Issue: Volume 8 / Issue 3 Pages: 470–489 ISSN: 29810221 DOI: 10.48309/JMPCR.2026.530850.1745 Scopus: View on Scopus Document Type: Article Authors and Affiliations Omar A., Department of Clinical Pathology, Faculty of Medicine, Al Azhar University, Cairo, Egypt; Elmalah A.A., Cardiology Department, Faculty of Medicine (for Girls), Al-Azhar University, Cairo, Egypt; Elkenany N.M., Cardiology Department, Faculty of M...