The egyptian clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

Theodor Bilharz Research Institute

Bibliographic Information

Authors: Fouad Y.; Esmat G.; Elwakil R.; Zakaria S.; Yosry A.; Waked I.; El-Razky M.; Doss W.; El-Serafy M.; Mostafa E.; Anees M.; Sakr M.A.; Abdelaty N.; Omar A.; Zaki S.; Al-Zahaby A.; Mahfouz H.; Abdalla M.; Albendary M.; Hamed A.-K.; Gomaa A.; Hasan A.; Abdel-Baky S.; El Sahhar M.; Shiha G.; Attia D.; Saeed E.; Kamal E.; Bazeed S.; Mehrez M.; Abdelaleem S.; Gaber Y.; Abdallah M.; Salama A.; Tawab D.; Nafady S.

Journal: Saudi Journal of Gastroenterology

Publisher: Wolters Kluwer Medknow Publications

Publication Date: January 2022

Volume / Issue: Volume 28 / Issue 1

Pages: 3–20

ISSN: 13193767

DOI: 10.4103/sjg.sjg_357_21

Scopus: View on Scopus

PubMed: 35083973

Document Type: Article

Access: All Open Access; Gold Open Access; Green Open Access

Authors and Affiliations

Fouad Y., Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Minia University, Egypt; Esmat G., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Elwakil R., Tropical Medicine Department, Faculty of Medicine, Ain Shams University, Egypt; Zakaria S., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Yosry A., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Waked I., Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Shebeen El Kom, Egypt; El-Razky M., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Doss W., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; El-Serafy M., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Mostafa E., Theodore Bilharz Research Institute, Cairo, Egypt; Anees M., Department of Gastroenterology and Hepatology; Sakr M.A., Tropical Medicine Department, Faculty of Medicine, Ain Shams University, Egypt; Abdelaty N., Tropical Medicine Department, Faculty of Medicine, Ain Shams University, Egypt; Omar A., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Zaki S., Department of Hepatogastroenterology and Infectious Diseases, Al-Azhar University, Cairo, Italy; Al-Zahaby A., Department of Hepatogastroenterology and Infectious Diseases, Al-Azhar University, Cairo, Italy; Mahfouz H., Department of Hepatogastroenterology and Infectious Diseases, Al-Azhar University, Assuit, Egypt; Abdalla M., Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt; Albendary M., Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Mansura University, Mansura, United States; Hamed A.-K., Department of Internal Medicine, Hepatology, and Diabetes, Egyptian Military Medical Academy, Cairo, Egypt; Gomaa A., Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt; Hasan A., Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Suez Canal University, Suez, Egypt; Abdel-Baky S., Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt; El Sahhar M., Egyptian Association for the Study of Liver and Gastrointestinal Disease (EASLGD), Police Medical Academy, Cairo, Egypt; Shiha G., Hepatology and Gastroenterology Unit, Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Attia D., Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt; Saeed E., Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Benha University, Benha, Egypt; Kamal E., Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Minia University, Egypt; Bazeed S., Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, South Valley University, Qena, Egypt; Mehrez M., Department of Hepatology, NTHMRI, Cairo, Egypt; Abdelaleem S., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Gaber Y., Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Abdallah M., Department of Medical Research Division Medicine, National Research Centre, Giza, Egypt; Salama A., Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt; Tawab D., Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assuit University, Assuit, Egypt; Nafady S., Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt

Abstract

The landscape of chronic liver disease in Egypt has drastically changed over the past few decades. The prevalence of metabolic-associated fatty liver disease (MAFLD) has risen to alarming levels. Despite the magnitude of the problem, no regional guidelines have been developed to tackle this disease. This document provides the clinical practice guidelines of the key Egyptian opinion leaders on MAFLD screening, diagnosis, and management, and covers various aspects in the management of MAFLD. The document considers our local situations and the burden of clinical management for the healthcare sector and is proposed for daily clinical practical use. Particular reference to special groups was done whenever necessary. © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

Keywords

Egyptian; Guidelines; MAFLD; Egypt; Humans; Mass Screening; Non-alcoholic Fatty Liver Disease; Prevalence; aldafermin; aramchol; belapectin; cilofexor; denifanstat; elfibrinor; enzyme inhibitor; lanifibrinor; obeticholic acid; pegbelfermin; peroxisome proliferator activated receptor agonist; pradigastat; recombinant fibroblast growth factor; saroglitazar; simtuzumab; tropixefor; unclassified drug; Article; awareness; bariatric surgery; clinical decision making; clinical practice; diet; echography; exercise; follow up; health care cost; health care policy; human; lifestyle modification; liver biopsy; liver cell carcinoma; liver cirrhosis; liver transplantation; metabolic fatty liver; nuclear magnetic resonance imaging; patient care; patient-reported outcome; portal hypertension; practice guideline; Ramadan fasting; treatment response; varicosis; nonalcoholic fatty liver

Citation Information

Scopus Citations: 39

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