Eosinophilic ascites as an uncommon presentation of eosinophilic gastroenteritis: A case report

Theodor Bilharz Research Institute

Bibliographic Information

Authors: El Ray A.; Montasser A.; El Ghannam M.; El Ray S.; Valla D.

Journal: Arab Journal of Gastroenterology

Publisher: Elsevier Ltd

Publication Date: June 2021

Volume / Issue: Volume 22 / Issue 2

Pages: 184–186

ISSN: 16871979

DOI: 10.1016/j.ajg.2021.02.002

Scopus: View on Scopus

PubMed: 34090834

Document Type: Article

Authors and Affiliations

El Ray A., Department of Hepatogastroenterology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Tropical Medicine and Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, Egypt, Service d'Hépatologie, Hôpital Beaujon, APHP, Clichy-la-Garenne, CRI-UMR 1149, Inserm and Université de Paris, Paris, France; Montasser A., Department of Hepatogastroenterology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Tropical Medicine and Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, Egypt, Service d'Hépatologie, Hôpital Beaujon, APHP, Clichy-la-Garenne, CRI-UMR 1149, Inserm and Université de Paris, Paris, France; El Ghannam M., Department of Hepatogastroenterology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Tropical Medicine and Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, Egypt, Service d'Hépatologie, Hôpital Beaujon, APHP, Clichy-la-Garenne, CRI-UMR 1149, Inserm and Université de Paris, Paris, France; El Ray S., Department of Hepatogastroenterology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Tropical Medicine and Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, Egypt, Service d'Hépatologie, Hôpital Beaujon, APHP, Clichy-la-Garenne, CRI-UMR 1149, Inserm and Université de Paris, Paris, France; Valla D., Department of Hepatogastroenterology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Pathology, Theodor Bilharz Research Institute, Giza, Egypt, Department of Tropical Medicine and Hepatogastroenterology, Faculty of Medicine, Cairo University, Cairo, Egypt, Service d'Hépatologie, Hôpital Beaujon, APHP, Clichy-la-Garenne, CRI-UMR 1149, Inserm and Université de Paris, Paris, France

Abstract

Background: Eosinophilic gastroenteritis (EGE) is defined by the presence of gastrointestinal symptoms, with an abnormal eosinophilic infiltrate of the intestine wall and exclusion of other causes of secondary eosinophilia. EGE has three clinical presentations, depending on the depth of eosinophilic infiltration of the bowel wall. It individualizes into three types, namely mucosal, muscular, and subserosal. Eosinophilic ascites, which is caused by edema and eosinophilic inflammation of the serosal layer of the small bowel wall, is the most uncommon presentation of EGE. Case summary: A 30-year-old Egyptian woman presented with pain in the epigastrium and diffuse abdominal distension. Past medical history comprised allergy to iron injections (for iron deficiency anemia). Clinical examination showed moderate abdominal distention (palpation) and shifting dullness (percussion) suggestive of moderate ascites; mild right pleural effusion was also suspected, but findings were otherwise unremarkable. Abdominal and pelvic examinations by ultrasound and contrast-enhanced computed tomography showed moderate ascites, mild right pleural effusion, and diffuse thickening of the antrum and small bowel loops. Endoscopy of the upper gastrointestinal tract revealed mild diffuse hyperemia of the esophagus, stomach and duodenum, with no relevant findings in the histopathology of biopsy specimens taken from these sites. Laboratory results showed eosinophilia in the peripheral blood and marked increase of eosinophils in the ascitic fluid. Treatment with corticosteroids resulted in normalization of the laboratory test results, and the ascites resolved within a week of initiation of therapy. Conclusion: Eosinophilic ascites, characterized by increased eosinophils in peripheral blood and ascitic fluid, showed dramatic response to steroid therapy. © 2021 Pan-Arab Association of Gastroenterology

Keywords

Case report; Corticosteroids; Eosinophilic ascites; Subserosal eosinophilic gastroenteritis; Adult; Ascites; Egypt; Enteritis; Eosinophilia; Female; Gastritis; Humans; C reactive protein; prednisone; abdominal distension; Article; ascites fluid; clinical article; clinical examination; computer assisted tomography; drug dose reduction; duodenitis; echography; Egyptian; eosinophil; eosinophilic gastroenteritis; epigastric pain; esophagitis; exudate; follow up; gastrointestinal biopsy; gastrointestinal endoscopy; histopathology; human; hyperemia; inflammatory infiltrate; microscopy; pleura effusion; smear; thorax radiography; vomiting

Citation Information

Scopus Citations: 5

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