Effect of some medicinal plant extracts as molluscicidal and apoptotic agents on biomphalaria Alexandrina snails

Theodor Bilharz Research Institute

Bibliographic Information

Authors: Ibrahim A.M.; Ghoname S.I.; Mansour S.M.; El-Dafrawy S.M.

Journal: Egyptian Journal of Aquatic Biology and Fisheries

Publisher: Egyptian Society for the Development of Fisheries and Human Health

Publication Date: 1 April 2020

Volume / Issue: Volume 24 / Issue 2

Pages: 291–300

ISSN: 11106131

DOI: 10.21608/ejabf.2020.80284

Scopus: View on Scopus

Document Type: Article

Access: All Open Access; Gold Open Access

Authors and Affiliations

Ibrahim A.M., Department of Environmental Research and Medical Malacology, Theodor Bilharz Research Institute, Egypt; Ghoname S.I., Department of Environmental Research and Medical Malacology, Theodor Bilharz Research Institute, Egypt; Mansour S.M., Department of Environmental Research and Medical Malacology, Theodor Bilharz Research Institute, Egypt; El-Dafrawy S.M., Department of Environmental Research and Medical Malacology, Theodor Bilharz Research Institute, Egypt

Abstract

Schistosomiasis is one of the neglected tropical diseases (NTDs). The freshwater snails Biomphalaria alexandrina are the intermediate host of Schistosoma mansoni in Egypt. Controlling these snails by medicinal plants is a promising way as it is ecofriendly strategy. The objective of this study is, to evaluate the molluscicidal activity of ethanolic extracts of three medicinal plants Ziziphus spina christi, Moringa oleifera, Tecoma stans and their effects on the chromosomes and apoptotic changes of B. alexandrina snails in control and exposed snails. Results showed that ethanolic extracts had a molluscicidal activity on B. alexandrina, where LC50 of Z. spina christi, M. oleifera and T. stans were 108.7, 209.4 and 256 mg/L respectively. The meiotic stages were detected in the normal control group, the first meiotic division begins with a long prophase (chromatin network), which is subdivided into four stages; leptotene, zygotene, pachytene, and diplotene. After exposure of each plant extract, there were some alterations in zygotene stage, which was different in all exposed snails and induced apoptotic changes was observed. Notably, Z. spina christi had more condensed zygotene stage than other two plants and significantly increased the percentage of apoptosis than control group. © Samuel K. K. Amponsah et al. 2020.

Keywords

Biomphalaria alexandrina; Chromosomes; Moringa oleifera; Schistosomiasis; Tecoma stans; Ziziphus spina christi

Citation Information

Scopus Citations: 3

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