Effects of three inorganic fertilizers on the biology and histopathology of infected Biomphalaria alexandrina snails

Theodor Bilharz Research Institute

Bibliographic Information

Authors: Hussein R.M.; Marie M.S.; Ali El-Deeb F.A.; Sayed S.M.

Journal: Research Journal of Pharmaceutical, Biological and Chemical Sciences

Publisher: Research Journal of Pharmaceutical, Biological and Chemical Sciences

Publication Date: 2016

Volume / Issue: Volume 7 / Issue 4

Pages: 2564–2574

ISSN: 9758585

Scopus: View on Scopus

Document Type: Article

Authors and Affiliations

Hussein R.M., Zoology Department, Faculty of Science, Cairo University, Giza, 12613, Egypt; Marie M.S., Zoology Department, Faculty of Science, Cairo University, Giza, 12613, Egypt; Ali El-Deeb F.A., Environmental Research and Medical Malacology Department, Theodor Bilharz Research Institute, Giza, Egypt; Sayed S.M., Environmental Research and Medical Malacology Department, Theodor Bilharz Research Institute, Giza, Egypt

Abstract

The present work was carried out to calculate the half lethal concentrations (LC50) of three inorganic fertilizers (balanced, high phosphorus and high nitrogen fertilizers) on Biomphalaria alexandrina snails and to demonstrate measurable effects on infected B. alexandrina with Schistosoma mansoni miracidia that were exposed for one week to 1/4 LC50 (126.4, 400 and 2375 ppm) separately of (balanced, high phosphorus and high nitrogen) fertilizers, respectively. The obtained results showed that the survival of all treated infected snail groups at the 1st shedding were significantly less than the control group. Moreover, results revealed a marked reduction in the infectivity of the infected snails especially those exposed to sublethal concentration of high nitrogen fertilizer when compared to control. In addition, the cercarial production of all treated groups was completely suppressed. These infected snails exhibited histopathological alterations, which is associated with severe damage in the digestive gland cells as well as the mother sporocysts of treated infected snails. Our study revealed the biological and histopathological effects of three inorganic fertilizers on infected Biomphalaria alexandrina snails.

Keywords

Biomphalaria alexandrina; Histopathology; Infection; Inorganic fertilizers; nitrogen fertilizer; phosphate fertilizer; adult; animal cell; animal experiment; animal model; animal tissue; Article; controlled study; exocrine gland; infection rate; LC50; nonhuman; schistosomiasis mansoni; sporocyst; survival rate

Citation Information

Scopus Citations: 5

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