Letter to the Editor: Urinary infection in European guidelines 2025 vs microbiology culture results in the management of urinary infection

Theodor Bilharz Research Institute

Bibliographic Information

Authors: Wishahi M.; Badawy M.

Journal: World Journal of Experimental Medicine

Publisher: Baishideng Publishing Group Inc

Publication Date: 20 June 2026

Volume / Issue: Volume 16 / Issue 2

Article No.: 115894

ISSN: 2220315X

DOI: 10.5493/wjem.v16.i2.115894

Scopus: View on Scopus

Document Type: Letter

Access: All Open Access; Gold Open Access; Green Open Access

Authors and Affiliations

Wishahi M., Department of Urology, Theodor Bilharz Research Institute, Cairo, 12411, Egypt; Badawy M., Department of Urology, Theodor Bilharz Research Institute, Cairo, 12411, Egypt

Abstract

We read with great interest the study by Yadav et al published in the World Journal of Experimental Medicine, which postulated a nomogram including patient’s critical factors, other than urine sample. European Association of Urology (EAU) published the guidelines on urological infection 2025. The EAU guidelines 2025 of urinary infections (UIs) has classified in two distanced categories: Localized UTs and systemic UTs according to specific patient’s symptoms and clinical signs, this new practical classification replaced previous concept of non-complicated urinary tract infection (UTI) against complicated UTI. The new EAU classification categorizes UIs as either localized or systemic, according to the presence of specific clinical signs and symptoms, this new practical classification replaced previous concept of non-complicated UTI against complicated UTI, irrespective of the results of bacteriological findings. In the new classification of UIs, the classification is based on clinical set-up on which the practitioner or urologist will manage the patient. Management of UIs is crucial to consider the urinary and gut microbiota. It was established recently that antibiotic use affects microbiota homeostasis in the gut and urinary tract that will initiate dysbiosis. © Author(s) 2026.

Keywords

Antibiotic; Metagenomics; Microbial communities; Microbiome; Probiotics; Urinary infection; Urine culture

Citation Information

Scopus Citations: 0

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